Clinically Tested Formulation

The scientific foundation that supports Amberen's effectiveness and safety is substantial and includes three randomized, double-blind, placebo-controlled clinical studies on menopausal and perimenopausal women and over 45 years of research on its main ingredients, succinates.

Choosing a clinically tested supplement is a relief on its own.

Amberen Clinical Trials

Amberen clinical trials are driven by the aim to improve women's quality of life during menopause.

Clinical evaluation of effectiveness and safety of supplement Amberen as a treatment for climacteric syndrome

Study design: Double-blind, randomized, placebo-controlled, 12-week study on 125 peri- and menopausal women of 42-60 years of age with mild to moderate menopause symptoms.

Results: Amberen was shown to be a safe and well-tolerated supplement with no registered side effects. Compared to the placebo group, women who took Amberen reported statistically significant improvements in many menopausal symptoms. The manuscript describing the results of this clinical trial is currently being prepared for publication.

Publications: Treatment of climacteric symptoms with an ammonium succinate-based dietary supplement: a randomized, double-blind, placebo-controlled trial. V. E. Radzinskii, I. V. Kuznetsova, Y. B. Uspenskaya, N. B. Repina, Y. K. Gusak, O. M. Zubova, D. I. Burchakov & A. A. Osmakova (2016) Gynecological Endocrinology, 32:sup2, 64-68, DOI: 10.1080/09513590.2016.1232686

Presentations: Oral presentation of the 2015/2016 Amberen clinical trial results By Y.B. Uspenskaya: International Menopause Society, 25th World Congress on Controversies in Obstetrics, Gynecology and Infertility, Amsterdam, Netherlands, November 10-13, 2016.
Clinical evaluation of effectiveness and safety of supplement Amberen as a treatment for climacteric syndrome

Study design: Double-blind, randomized, placebo-controlled, 12-week study on 102 peri- and menopausal women between 42 and 60 years of age with mild to moderate menopause symptoms.

Results: Compared to the placebo group, many menopause symptoms showed statistically significant improvement in women who took Amberen. The results of the safety evaluation proved Amberen to be a safe dietary supplement.

Publications: Kuznetsova I.V. UYB, Borisova N.I., Zhukova E.V., Berdnikova N.G., Gusak Yu.K. Akusherstvo i ginekologiya/Obstetrics and Gynecology. Effectiveness of alternative therapy in perimenopausal and postmenopausal women (in Russian). Akusherstvo i ginekologiya/Obstetrics and Gynecology. 2016 5:126 - 33.

Effectiveness and safety of using a succinate-based dietary supplement for women in menopause. Kuznetsova I.V, Uspenskaya Yu. B., Borisova N.I, , Zhukova E.V., Berdnikova N.G., Gusak Yu. K Effectiveness and safety of using a succinate-based dietary supplement for women in menopause. Medline.ru, 2016, Vol 17, Art. 3, p 24-45 (Mecine.ru/pdf)

Presentations: Poster presentation at the 15th World Congress on Menopause. Effectiveness and safety of using Amberen supplementation in perimenopausal and postmenopausal women.Yu. Uspenskaya, I. Kuznetsova, N. Borisova, N. Berdnikova and U. Gusak
Evaluation of Enerlit-Clima (equivalent of Amberen's formulation) as a treatment for climacteric syndrome

Study design: This double-blind, randomized, placebo-controlled, 3-week study involved 70 menopausal women.

Results: The results of the study demonstrated that Enerlit-Clima-based therapy helps alleviate many menopause symptoms when compared with the placebo group. No adverse side effects of Enerlit-Clima were registered.

Publications: Maevsky, E. I., et al. "A succinate-based composition reverses menopausal symptoms without sex hormone replacement therapy.” Advances in gerontology= Uspekhi gerontologii/Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo 21.2 (2008): 298-305.

Clinical evaluation of effectiveness and safety of supplement Amberen as a treatment for climacteric syndrome

Study design: Double-blind, randomized, placebo-controlled, 12-week study on 125 peri- and menopausal women of 42-60 years of age with mild to moderate menopause symptoms.

Results: Amberen was shown to be a safe and well-tolerated supplement with no registered side effects. Compared to the placebo group, women who took Amberen reported statistically significant improvements in many menopausal symptoms. The manuscript describing the results of this clinical trial is currently being prepared for publication.

Publications: Treatment of climacteric symptoms with an ammonium succinate-based dietary supplement: a randomized, double-blind, placebo-controlled trial. V. E. Radzinskii, I. V. Kuznetsova, Y. B. Uspenskaya, N. B. Repina, Y. K. Gusak, O. M. Zubova, D. I. Burchakov & A. A. Osmakova (2016) Gynecological Endocrinology, 32:sup2, 64-68, DOI: 10.1080/09513590.2016.1232686

Presentations: Oral presentation of the 2015/2016 Amberen clinical trial results By Y.B. Uspenskaya: International Menopause Society, 25th World Congress on Controversies in Obstetrics, Gynecology and Infertility, Amsterdam, Netherlands, November 10-13, 2016.

Clinical evaluation of effectiveness and safety of supplement Amberen as a treatment for climacteric syndrome

Study design: Double-blind, randomized, placebo-controlled, 12-week study on 102 peri- and menopausal women between 42 and 60 years of age with mild to moderate menopause symptoms.

Results: Compared to the placebo group, many menopause symptoms showed statistically significant improvement in women who took Amberen. The results of the safety evaluation proved Amberen to be a safe dietary supplement.

Publications: Kuznetsova I.V. UYB, Borisova N.I., Zhukova E.V., Berdnikova N.G., Gusak Yu.K. Akusherstvo i ginekologiya/Obstetrics and Gynecology. Effectiveness of alternative therapy in perimenopausal and postmenopausal women (in Russian). Akusherstvo i ginekologiya/Obstetrics and Gynecology. 2016 5:126 - 33.

Effectiveness and safety of using a succinate-based dietary supplement for women in menopause. Kuznetsova I.V, Uspenskaya Yu. B., Borisova N.I, , Zhukova E.V., Berdnikova N.G., Gusak Yu. K Effectiveness and safety of using a succinate-based dietary supplement for women in menopause. Medline.ru, 2016, Vol 17, Art. 3, p 24-45 (Mecine.ru/pdf)

Presentations: Poster presentation at the 15th World Congress on Menopause. Effectiveness and safety of using Amberen supplementation in perimenopausal and postmenopausal women. Yu. Uspenskaya, I. Kuznetsova, N. Borisova, N. Berdnikova and U. Gusak

Evaluation of Enerlit-Clima (equivalent of Amberen's formulation) as a treatment for climacteric syndrome

Study design: This double-blind, randomized, placebo-controlled, 3-week study involved 70 menopausal women.

Results: The results of the study demonstrated that Enerlit-Clima-based therapy helps alleviate many menopause symptoms when compared with the placebo group. No adverse side effects of Enerlit-Clima were registered.

Publications: Maevsky, E. I., et al. "A succinate-based composition reverses menopausal symptoms without sex hormone replacement therapy." Advances in gerontology= Uspekhi gerontologii/Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo 21.2 (2008): 298-305.

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The statements on this website have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Every woman is unique and every woman experiences menopause and its symptoms differently. Your experience with Amberen will be unique as well. The statements we make regarding Amberen's menopausal symptom relief benefits are supported by the results of ingredient manufacturer sponsored randomized, double-blind, placebo-controlled, human clinical trials, including two recent clinical trials dating from 2014-15 and 2015-16, involving 102 and 125 menopausal women, aged 42-60 years, with mild to moderate menopausal symptoms, evaluating the efficacy of Amberen® in the treatment of climacteric complaints over the course of 90 days. Both of the studies' results showed that Amberen helped restore hormonal balance and that when compared with placebo users experienced statistically significant relief from common menopausal symptoms, including, but not limited to, hot flashes, night sweats, irritability, mood swings (as measured by relief from "feeling unhappy and depressed", "crying spells", and "loss of interest in most things" symptomologies), weight management (as measured by changes in weight, BMI, and hip and waist circumference analyses), difficulty sleeping, stress and anxiety, difficulty concentrating, fatigue and low energy, headaches, muscle and joint aches and loss of sexual interest. Statistically significant results typically occurred between 30 through 90 days of continuous use.

No adverse side effects were observed during clinical studies. USE ONLY AS DIRECTED. Caution: Amberen is not intended for use by pregnant or nursing women. Do not take if you have severe hypertension. If you are taking prescription medication or have any medical condition, consult your doctor before use. Discontinue use and consult your doctor if you have any adverse reaction.

*** Individual results will vary. Regarding the endorsements and testimonials provided on this website, please note that while they represent individual, real life experiences of women who have used Amberen, they are individual results and may not reflect the typical results that other users will experience. We do not make any claims or assurances that these individual experiences represent the typical results that Amberen consumers will achieve. See above for information regarding typical results as shown in clinical trials. Video testimonials were compensated for their participation. These endorsements and testimonials are provided as a means for customers to share their experiences using Amberen with other women, and are not provided or intended to be interpreted as claims that Amberen will provide the same benefits to all customers. The endorsements and testimonials are displayed verbatim except where edited for privacy reasons, length or to correct grammatical or typing errors, and not all endorsements or testimonials are shown in their entirety as privacy concerns, space availability and relevancy at times require minor editing prior to being displayed. Endorsements and testimonials are never edited, however, in a way that would change their substantive meaning or essence.

Based on survey conducted on www.amberen.com between July and September 2015 of 1103 actual Amberen customers who completed a 90-day course who responded "Yes" to the question "Did Amberen work for you in relieving menopause symptoms?" Star rating based on 1,000+ reviews as of 09.07.2016 on ResellerRatings.com.

‡Individual results will vary. Actual Amberen customer who was reimbursed for costs related to appearance.

NurseAid agents do not provide medical advice and should never be used as a substitute or alternative to seeking professional medical advice and treatment.

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